It's still all going to boil down to a different method of doing the same kind of things, because they'll be governed by the same physical laws.
Of course, we're assuming here that they haven't come up with an alternative, completely different system that explains the universe and its laws just as well but without using anything like we know of. I guess at the end of the day that's all our system is describing, the universe as we perceive it.
I know it's easy for me to say in hindsight, but that's kind of what I was trying to get at