That would be stupid if it didn't work. I've bought stuff all over the net with my Visa debit card, I kinda figure as a big music provider they would let you use debit cards on iTunes... I don't really like their setup though. It downloads a copy protected one that you can only use if you have a password on iTunes... So if you need to use it in say a video that you were editing or whatever, you couldn't... I'd rather just buy the whole CD...