The first ATI cards will use the R600 core. It's gonna be the X2000 series, from the X2000GT to the X2900XTX. It's slated for a Q1 2007 release, most likely in March.
Microsoft Flight Simulator X already works with DirectX 10. Games will be coming out throughout this year, but most do not have official release dates.
Here's some benchmarks with the 8800GTX:
I don't think anyone has any R600 benchmarks yet.