You can get these from www.filehippo.com
Spybot search & distroy
This reg cleaner is the best I've seen in a good while >>>
Don't get the disk cleaner. It's not user friendly.
When you get the first group of programs, updated them first thing. Then go to safe mode and run them. The reg cleaner can be run from safe mode also.
It's best to run them all a second or third time as some tools won't get all of the bad stuff in just one pass.
You can also run the internet tools from the IE tools list in safe mode. Then run the built in disk cleaner and defrag.
Boot back to normal mode and see if that helps.
Quick question. Do you have a firewall and antivirus on that system?