Yes, and also if you have a sound card, and your mobo had one, in some cases when you reboot, the operating system installs the driver of the other device and sound is directed to that device and not the one you previously had.
Asus P4P800 SE
Intel P4 3.2 Gig 1024 Meg PC3200 cas latency 2.5
RAID 0 2-36.7 Gig SATA WD 10,000 RPM
200 Gig WD ATI ALL-IN-WONDER 9600XT
6500 Kb bandwith Internet Connection