Ok well you cannot use RAID 10 because this array needs 4 hard disks and you will loose your OS install. RAID 10 will not work with 3 HD's. So it's either create a RAID 10 array, and loose your Vista OS in the process, then re-install the OS onto the RAID 10 array. Or consider the option below. And because you have an OS on one HD you have limited the arrays available to you.
I can make a suggestion though.
Why not RAID 0 the 160GB HD's...
... and RAID 1 the 500GB HD's?
You can then use the RAID 0 array for your OS and applications, faster loading times. And you can protect all your important stuff on your RAID 1 array. This means re-installing OS too.
Or RAID 1 the 500GB HD's. Leave the OS on the one drive and install applications on the other 160GB drive. This way you can keep your OS that you installed.