I reckon your using a bad audio driver. I do music too and use ASIO drivers where I can.
When you install ASIO4ALL you have to adjust it's buffers to give you a smooth audio output without drop-outs.
If you already have an ASIO driver on your audio interface then go into the settings and adjust the size of the buffers.
Also there's a few things you can do to the computer to streamline it for audio production. And it looks like your OS isn't accessing all you RAM for some reason.
Whats your system specs?