I think this question is entirely dependant on what you want your whole comptuer for.
If it's for general home use browsing the web, emailing and watchign films etc then your safe with pretty much any motherboard really (but read reviews) as long as they are compatible with your processor and RAM.
What do you plan on using the computer for? Also do you already have a processor and graphics card setup in mind?
He who has never failed has never attempted anything worth succeeding at.
Dont Eat Animals, Its Not Good For Them And They Dont Like It!