You have way too many instances of Google Chrome running, what is going on there?
Also, I see you have Norton's AV-- a notorious resource hog. I'd switch to Avast! or Microsoft Security Essentials.
Spiceworks is a network monitoring tool Are you aware that you have it installed?
Do you have a Creative Labs device that you plug into your computer? If you no longer use that device, then you can get rid of those.
Chrome spawns additional threads when you have multiple tabs open. This is normal behavior of Chrome. Those threads will remain even with one tab open, just to handle the additional overhead of more tabs should you open them again.
Norton's AV is likely the culprit behind excessive memory usage, and Spiceworks could be part of it too, but only if he has a large home network that he's trying to monitor and scan. Here at work, where there are hundreds of devices, Spiceworks only uses 365MB of RAM. At home, Spiceworks uses 209 MB of RAM on my server.
Creative's software, as much as I dislike their stability issues, is likely not the memory hog.