Erm, i've fought that battle before with my dad's computer.. and eventually I won.
I have no idea how though.. I would just keep changing the resolution back and it stopped bothering me...
Maybe a virus? Run crapcleaner and (you don't need to but go ahead and run) reg cleaner and some virus scan (I had AVG FREE)
I think that was around when he was having problems with IE. I don't know, his computer is so S.
BAD! It's one of those $400 from walmart.. the use-for-ayear and throw away. It's been 6 years :P That means this computer is 8 years old! wow!
And the mouse was skipping too..
Have you uninstalled anything lately or installed something? Maybe something you say will refresh my memory.