unless you saved the picture as tiff on your camera it would not make any diff. Some cameras offer this option. In my opinion no point to change to tiff from jpeg unless your goin to copy to another cd and then copy this cd to another. If you going to make only 4x6 your just waisting your time. If you whant good quality pictures just print straight from your card. If you copy your pictures to cd your quality diminish at printing.