If I had to run all that list of software to feel "safe" or "sure" while surfing the web, I'd turn my computer off and walk away from it because it simply wouldn't be worth my time to keep up with all of that. Not to mention that I have multiple computers which would make the task even more arduous.
If you use your computer for banking or you have important files in there, I think it's worth the effort. You could just select one of the many computers you own and do it only there. It would be a shame if something bad happened and you could have avoided it just by setting up a few programs.