niiko101
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2x 4GB sticks is best option, Because occupying all 4 memory slots puts a lot of stress on the motherboard. If you felt the need for more memory they do make 2x 8GB RAM (but they are really expensive). The Difference between a mid town and a full tower, Is size of the motherboard that fits in it, there are M-ATX, ATX, E-ATX and XL-ATX and in a mid tower case only M-ATX and standard ATX motherboards fit in, Full size cases can fit the rest, But only a few full size cases can fit XL-ATX.