Nope. I actually got a new case a few days ago and installed the mobo with no problem. I didn't notice anything unusual at all considering I dusted and cleaned it heavily. BTW, the problems started before I switched cases.
The board is hitting 5+ years or so, but it looks fine and I haven't noticed anything unusual about it. I was planning on upgrading my motherboard but noticed that not many have an AGP slot still, and since I just bought my ATI about a year ago I don't want to upgrade that to a PCIe and waste money since the ATI is serving it's purpose fine.