I haven't used it to clear them as I have a batch file that clears them on each boot. You can also use spiderbite. Here is the batch file for the boot clean.
In Win2K or WinXP, deleting Index.dat -- even systemwide for ALL users! -- without coughing up money for any commercial software, is a snap. Here's how:
In the Registry, go to this key:
HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Windows\CurrentVersion\RunOnce
and insert a new String Value (call it ZapIndex if you like). In the data for ZapIndex, put this command:
%ComSpec% /c del /s /q "C:\Documents and Settings\index.dat"
You can also put this command into a batch file, such as ZAPINDEX.BAT (or .cmd) and store it hidden in the root of the C: drive. Then the registry key can simply call that program:
%ComSpec% /c C:\ZapIndex.bat
If you store this value in the RUnOnce key, it will do just that: run once at the nexrt reboot of the machine. If you want it to run daily, put it into the Run key instead of RunOnce
Use notepad and create a file called Zapindex and put it in C: root. then copy this into it.
%ComSpec%/c del/s/q "C:\Documents and Settings\index.dat"